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Obstructive sleep apnea (OSA) and diabetes has been known to be closely related to each other and both diseases impact highly on the public health. There are many evidence of reports that OSA is associated with diabetes with a bidirectional correlation. A possible causal mechanism of OSA to diabetes is intermittent hypoxemia and diabetes to OSA is microvascular complication. However, OSA and diabetes have a high prevalence rate in public and shares the common overlap characteristic and risk factors such as age, obesity, and metabolic syndrome that make it difficult to establish the exact pathophysiologic mechanism between them. In addition, studies demonstrating that treatment of OSA may help prevent diabetes or improve glycemic control have not shown convincing result but have become a great field of interest research. This review outlines the bidirectional correlation between OSA and diabetes and explore the pathophysiologic mechanisms by approaching their basic etiologies.

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• Duration of dual-antiplatelet therapy after stent-assisted coil for unruptured intracranial aneurysm: A nationwide cohort study
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• Risk of dementia in survivors of active tuberculosis in Korea: A nationwide cohort study
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• Incidence and Clinical Characteristics of Slipped Capital Femoral Epiphysis in Patients with Endocrinopathy
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  Journal of Bone and Joint Surgery.2024; 106(5): 381.     CrossRef
• A nationwide study of regional preference and graft survival of kidney transplantation in South Korea: patterns of centralization in the capital area
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• Migraine is associated with the development of adult patients with inflammatory bowel disease: a nationwide, population-based study
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• Association between age at diagnosis of type 2 diabetes and cardiovascular morbidity and mortality risks: A nationwide population-based study
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• Trends in Healthy Life Expectancy (HALE) and Disparities by Income and Region in Korea (2008–2020): Analysis of a Nationwide Claims Database
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• Association of temporal change in body mass index with sudden cardiac arrest in diabetes mellitus
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• Trend in the Incidence of Severe Partial Edentulism among Adults Using the Korean National Health Insurance Service Claim Data, 2014–2018
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• Real-World Impact of Modern Reperfusion Therapy for Acute Ischemic Stroke : A Nationwide Population-Based Data Study in Korea
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• All-cause and cause-specific mortality in patients with Behçet disease versus the general population
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• Risk of incident chronic kidney disease among patients with urolithiasis: a nationwide longitudinal cohort study
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• Clinical benefits of surgical ablation during isolated aortic valve replacement: a nationwide study
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• Risk of Cardiovascular Disease according to Baseline Low-Density Lipoprotein Cholesterol Level in Different Age Groups in Korean Diabetes Population: A Cohort Study
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• The Association of Body Mass Index and Waist Circumference with Sepsis-Related Mortality in South Korea
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• An Ensemble Feature Selection Approach-Based Machine Learning Classifiers for Prediction of COVID-19 Disease
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• Korea4K: whole genome sequences of 4,157 Koreans with 107 phenotypes derived from extensive health check-ups
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• Clinical and economic burden of immune tolerance induction in entire patients with hemophilia A: Insights from a real-world Korean setting
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• Beyond Symptoms: Radiologic identification of asymptomatic Mycobacterium avium complex pulmonary infections
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• Association between migraine and the risk of vascular dementia: A nationwide longitudinal study in South Korea
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• Incidence and prevalence of seropositive rheumatoid arthritis among Korean women of childbearing age: a nationwide population-based study
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• Myth and Truth in Opioid Consumption with Intrathecal Morphine Pump Implantation in Chronic Pain: A Retrospective Cohort Study with Claims Database in South Korea
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• Epidemiology of idiopathic sudden sensorineural hearing loss in the era of big data
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• Allergic Diseases and Risk of Incident Dementia and Alzheimer's Disease
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• Post-operative recurrence of liver cancer according to antiviral therapy for detectable hepatitis B viremia: A nationwide study
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• Comparable Mortality Between Asian Patients with Chronic Hepatitis B Under Long-Term Antiviral Therapy vs Matched Control: A Population-Based Study
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• Body mass index, waist circumference and cardiovascular diseases in transitional ages (40 and 66 years)
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• Waist circumference and end‐stage renal disease based on glycaemic status: National Health Insurance Service data 2009–2018
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• Comparison of Trends in the Incidence of Traumatic Spinal Cord Injury in Daily Life, Automobile Accidents, and Industrial Accidents: A National Multi-Insurance Study in Korea
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• A population-based study on the risk of prescription opioid abuse in patients with chronic opioid use and cost-effectiveness of prescription drug monitoring program using a patient simulation model in South Korea
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• The effects of sociodemographic factors on help-seeking for depression: Based on the 2017–2020 Korean Community Health Survey
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• Efficacy of acupuncture on cardiovascular complications in patients with diabetes mellitus in Korea: A nationwide retrospective cohort
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• A 12-year nationwide cohort study on the association between central retinal artery occlusion and cancer
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• Long-Term Nonoperative Management is Associated With Lower Mean 9-Year Follow-Up Survival Compared to Total Knee Arthroplasty in Knee Osteoarthritis Patients—Survival Analysis of a Nationwide South Korean Cohort
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• Positive faecal immunochemical test predicts the onset of inflammatory bowel disease: A nationwide, propensity score-matched study
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• Early and long-term outcomes of bioprosthetic versus mechanical tricuspid valve replacement: A nationwide population-based study
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• Association of general and central obesity, and their changes with risk of knee osteoarthritis: a nationwide population-based cohort study
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• Histamine-2 Receptor Antagonists and Proton Pump Inhibitors Are Associated With Reduced Risk of SARS-CoV-2 Infection Without Comorbidities Including Diabetes, Hypertension, and Dyslipidemia: A Propensity Score-Matched Nationwide Cohort Study
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• Increased risk of cardiovascular disease associated with diabetes among adult cancer survivors: a population-based matched cohort study
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• Participation and Prognostic Impact of Cardiac Rehabilitation After Acute Coronary Syndrome: Big-Data Study of the Korean National Health Insurance Service
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• Analysis of Anxiety or Depression and Long-term Mortality Among Survivors of Out-of-Hospital Cardiac Arrest
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• Treatment Changes and Prognoses in Patients with Incident Drug-Induced Parkinsonism Using a Korean Nationwide Healthcare Claims Database
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• Trends in the Incidence and Etiology of Non-Traumatic Spinal Cord Injury in Korea: A Nationwide Population-Based Study From 2007 to 2020
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• The Association between Metabolic Syndrome and Epithelial Cell Abnormalities Detected on Pap Smear: A Nationwide Population-Based Study
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• Long‐term adverse neurodevelopmental outcomes of discordant twins delivered at term: A nationwide population‐based study
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• Cancer and Mortality Risks of Graves’ Disease in South Korea Based on National Data from 2010 to 2019
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• Association of Waist Circumference with the Risk of Inflammatory Bowel Disease: a Nationwide Cohort Study of 10 Million Individuals in Korea
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• Lifestyle factors and long-term survival in patients with chronic non-cancer pain: a nationwide cohort study in South Korea
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• Long term renal outcome after hypertensive disease during pregnancy: a nationwide population-based study
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• Lower risk of depression after smoking cessation and alcohol abstinence in patients with gastric cancer who underwent gastrectomy: A population‐based, nationwide cohort study
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• Acute Pancreatitis and the Risk of Dementia in Diabetes: A Nationwide Cohort Study Using Korean Healthcare Claims Database
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• Impact of mental disorders on the risk of heart failure among Korean patients with diabetes: a cohort study
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• Higher Non-High-Density Lipoprotein Cholesterol Was Higher Associated With Cardiovascular Disease Comparing Higher LDL-C in Nine Years Follow Up: Cohort Study
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• Impact of Allergic Disease on the Risk of Mycobacterial Disease
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• Trends in the Prevalence of Blindness and Correlation With Health Status in Korean Adults: A 10-Year Nationwide Population-Based Study
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• Bovine pericardial versus porcine bioprosthetic mitral valves: results from a Korean Nationwide Cohort Study
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• Association between preoperative modifiable lifestyle factors and mortality after cancer surgery: a population-based cohort study in South Korea
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  Annals of Surgical Treatment and Research.2023; 105(4): 179.     CrossRef
• Classification of long-term clinical course of Parkinson’s disease using clustering algorithms on social support registry database
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  Journal of Big Data.2023;[Epub]     CrossRef
• Association between Proteinuria Status and Risk of Hypertension: A Nationwide Population-Based Cohort Study
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• Association of physical activity with the risk of Parkinson's disease in depressive disorder: A nationwide longitudinal cohort study
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  Journal of Psychiatric Research.2023; 167: 93.     CrossRef
• Effect of changes in the hearing aid subsidy on the prevalence of hearing loss in South Korea
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• Preoperative Body Mass Index, Waist Circumference, and Mortality After Major Cancer Surgery: A Nationwide Cohort Study in Korea
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  Journal of Korean Medical Science.2023;[Epub]     CrossRef
• Characteristics and risk factors of suicide among people who attempted self-harm in South Korea: A longitudinal National Cohort Study in South Korea
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• Association Between Premature Menopause and Cardiovascular Diseases and All‐Cause Mortality in Korean Women
  Gyu Bae Lee, Ga Eun Nam, Wonsock Kim, Byoungduck Han, Kyung Hwan Cho, Seon Mee Kim, Youn Seon Choi, Do Hoon Kim, Yong‐Gyu Park, Jin‐Hyung Jung, Kyungdo Han, Yang‐Hyun Kim
  Journal of the American Heart Association.2023;[Epub]     CrossRef
• Risk of gastric cancer among long-term proton pump inhibitor users: a population-based cohort study
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  European Journal of Clinical Pharmacology.2023; 79(12): 1699.     CrossRef
• Cancer Risk in Elderly Korean Patients with Neurodegenerative Disease and its relation to Type 2 Diabetes
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• Performance of Cardiovascular Risk Prediction Models in Korean Patients With New‐Onset Rheumatoid Arthritis: National Cohort Study
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• Impact of Propofol-based Total Intravenous Anesthesia Versus Inhalation Anesthesia on Long-term Survival After Cancer Surgery in a Nationwide Cohort
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• Bovine pericardial versus porcine bioprosthetic aortic valves: A nationwide population-based cohort study in Korea
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• Decreased Risk of Knee Osteoarthritis with Taller Height in an East Asian Population: A Nationwide Cohort Study
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  Journal of Clinical Medicine.2023; 13(1): 92.     CrossRef
• Cost-effectiveness of the anti-vascular endothelial growth factor intravitreal injection and panretinal photocoagulation for patients with proliferative diabetic retinopathy in South Korea
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• Prior Evaluation of Nutritional Status and Mortality in Patients with Sepsis in South Korea
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• Increased Risk of Hip Fracture in Patients with Acromegaly: A Nationwide Cohort Study in Korea
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• Cancer risks in patients with ankylosing spondylitis and the effects of biologic agents: a population-based study
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• Proton Pump Inhibitor Co-Therapy in Patients with Atrial Fibrillation Treated with Oral Anticoagulants and a Prior History of Upper Gastrointestinal Tract Bleeding
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• Institutional case volume-incorporated mortality risk prediction model for cardiac surgery
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• Does Surgical Ablation of Atrial Fibrillation Benefit Patients Undergoing Bioprosthetic Valve Replacement?
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  Seminars in Thoracic and Cardiovascular Surgery.2022; 34(3): 906.     CrossRef
• Burden of comorbidities and medication use in childbearing women with rheumatic diseases: a nationwide population-based study
  Min Kyung Chung, Chan Hee Lee, Jin Su Park, Hyunsun Lim, Jisoo Lee
  The Korean Journal of Internal Medicine.2022; 37(6): 1250.     CrossRef
• Validation of Dynamic Aspartate‐to–Alanine Aminotransferase Ratio for Predicting Liver Disease Mortality
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• Blood Pressure Levels and Risks of Dementia: a Nationwide Study of 4.5 Million People
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• Liver enzymes and risk of ocular motor cranial nerve palsy: a nationwide population-based study
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• Underutilisation of prophylactic G-CSF in breast cancer patients receiving adjuvant docetaxel/cyclophosphamide chemotherapy
  Minhee Ku, Nam Kyung Je
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• Epidemiologic study of bladder and urethral injury in Korea: A nationwide population-based study
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• Pericardial Versus Porcine Valves for Surgical Aortic Valve Replacement
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• Effect of obesity and metabolic health on urolithiasis: A nationwide population-based study
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• Development of eClaim system for private indemnity health insurance in South Korea: Compatibility and interoperability
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  Journal of Neurotrauma.2022; 39(5-6): 390.     CrossRef
• Female Reproductive Factors and the Risk of Bronchiectasis: A Nationwide Population-Based Longitudinal Study
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  Biomedicines.2022; 10(2): 303.     CrossRef
• Clinical outcomes of early closure versus conservative strategy after diagnosis with atrial septal defect: a nationwide population-based cohort study
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• Risk of Osteoporotic Fractures Among Obese Women Based on Body Mass Index and Waist Circumference: A Nationwide Cohort in South Korea
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  Resuscitation.2022; 173: 31.     CrossRef
• Blood pressure and mortality after percutaneous coronary intervention: a population-based cohort study
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• Hip Fracture Risk According to Diabetic Kidney Disease Phenotype in a Korean Population
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  Journal of Personalized Medicine.2022; 12(8): 1260.     CrossRef
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• Physical performance and chronic kidney disease development in elderly adults: results from a nationwide cohort study
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• Pre-transplant depression decreased overall survival of patients receiving allogeneic hematopoietic stem cell transplantation: a nationwide cohort study
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• The Population Prevalence, Associations of Congenital Heart Defect and Mortality Risk for Down’s Syndrome in South Korea Based on National Health Insurance Service (NHIS) Data

  
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• Prognostic value of long-term gamma-glutamyl transferase variability in individuals with diabetes: a nationwide population-based study
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• Improved oral hygiene is associated with decreased risk of new-onset diabetes: a nationwide population-based cohort study
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• Development of stroke identification algorithm for claims data using the multicenter stroke registry database
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• The Risk of Myocardial Infarction and Ischemic Stroke According to Waist Circumference in 21,749,261 Korean Adults: A Nationwide Population-Based Study
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• Severe hypoglycemia and the risk of cardiovascular disease and mortality in type 2 diabetes: a nationwide population-based cohort study
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